Creatine Kinase Isoenzyme Detection Reagent(CK-MB)
(Immunofluorescence Chromatography) Clinical Significance
CK-MB Overview
Creatine kinase isoenzyme (CK-MB) is an enzyme system that widely
exists in human rhabdoid muscle. When the rhabdoid muscle, such as
myocardium and skeletal muscle, is injured, the creatine kinase
isoenzyme will be released into the blood, and it will start to
rise in 4-6 hours, the peak time is 24 hours, and the recovery time
is 48-72 hours.
CK-MB performance index
| Detection range | sample size | Sample type | Test time |
| 0.8~100ng/mL | 60μl | Whole blood / serum / plasma | 15min |
CK-MB Clinical significance
- AMI was diagnosed early and risk stratified
- Estimate infarct size or reinfarct size
- The most valuable marker of MI is non-ST elevation
CK-MB Clinical value
The isozyme of creatine kinase plays an important role in clinical
diagnosis. The level of creatine kinase in human serum increases
rapidly during the occurrence of various diseases including muscle
atrophy and myocardial infarction. It is believed that the activity
of creatine kinase can be measured more reliably than
electrocardiogram in the diagnosis of myocardial infarction. In
myocardial infarction, creatine kinase is elevated within 6 hours
of onset, peaks at 24 hours, and returns to normal within 3-4 days.
Among them, the creatine kinase isoenzyme CK-MB has the highest
diagnostic specificity. Creatine kinase has attracted extensive
attention and in-depth research because of its important
physiological function and clinical application value
CK-MB Normal value
- Electrophoretic method: CK-MB<0.05 (CK-MB<5%) CK-MM>0.94 ~
0.96 (CK-MM>94% ~ 96%) CK-BB no or trace (CK-BB no or trace)
- Enzyme rate method (37℃) CK-MB: 0 ~ 18U/L CK-MM: 0 ~ 18U/L CK-BB:
0U/L.
Application Department
Cardiology, emergency, laboratory, pediatrics, hematology,
oncology, Nephrology, surgery, etc
CK-MB Clinical comparison
MYO Clinical Comparison
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise
engaged in the research and development, production and operation
of in vitro diagnostic products. The in vitro diagnostic products
developed by the company cover POCT series, microbial series,
biochemical series and immune series reagents and supporting
instruments.
The company has always adhered to the core concept of "fast and
accurate, living up to life", committed to providing society with
excellent products and services, and contributing to the cause of
human health.
