Myoglobin Detection Reagent(MYO)(Immunofluorescence Chromatography)
Clinical Significance
MYO Overview
Myoglobin (MYO) is a hemoglobin that is present in cardiac muscle
and skeletal muscle cytoplasm and is not present in smooth muscle.
Myoglobin can be detected in the blood 1-2 hours after the onset of
AMI, which is one of the earliest markers representing the
elevation of myocardial injury. Myo is abundant in myocardium and
skeletal muscle, and is quickly released into the blood during AMI.
It is highly sensitive to AMI
MYO performance index
| Detection range | sample size | Sample type | Test time |
| 10~300ng/mL | 60μl | Whole blood / serum / plasma | 15min |
MYO Three-level structure
The myoglobin molecule is a flat prism with a molecular size of
about 4.5mm×3.5mm×2.5m. The polypeptide backbone in the molecule is
composed of 8 straight a-helices of varying lengths. The longest
helix contains 23 residues and the shortest 7 residues. Almost 80%
of the amino acid residues in the molecule are in the α-helix
region. . These 8 spirals are named A, B, C...H respectively. The
corresponding non-helical region peptides are called NA (terminal
section), AB, BC,...FG, GH, HC (C-terminal section). Therefore,
each residue has a sequence number calculated from the N-terminus.
In addition to the position in each helical segment, an additional
number is given. For example, the 93rd His is coded as F8, which
means that His is at the 8th position of the F helix.
MYO Clinical significance
- Early AMI excludes the most important and sensitive indicators
- Recurrent diagnosis of AMI, the best index of reperfusion treatment
effect evaluation
Application Department
Cardiology, emergency, laboratory, pediatrics, hematology,
oncology, Nephrology, surgery, etc
MYO Clinical Comparison
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise
engaged in the research and development, production and operation
of in vitro diagnostic products. The in vitro diagnostic products
developed by the company cover POCT series, microbial series,
biochemical series and immune series reagents and supporting
instruments.
The company has always adhered to the core concept of "fast and
accurate, living up to life", committed to providing society with
excellent products and services, and contributing to the cause of
human health.
